Structural Formula Vector Image
Title: Embramine
CAS Registry Number: 3565-72-8
CAS Name: 2-[1-(4-Bromophenyl)-1-phenylethoxy]-N,N-dimethylethanamine
Additional Names: 2-[(p-bromo-a-methyl-a-phenylbenzyl)oxy]-N,N-dimethylethylamine; [2-(1-p-bromophenyl-1-phenylethoxy)ethyl]dimethylamine; 2-[1-(4-bromodiphenyl)ethoxy]-N,N-dimethylethylamine; p-bromo-a-methylbenzhydryl 2-dimethylaminoethyl ether; 1-(p-bromophenyl)-1-phenyl-1-(2-dimethylaminoethoxy)ethane; b-dimethylaminoethyl p-bromo-a-methylbenzhydryl ether
Molecular Formula: C18H22BrNO
Molecular Weight: 348.28
Percent Composition: C 62.07%, H 6.37%, Br 22.94%, N 4.02%, O 4.59%
Literature References: Prepn: L. Novak, M. Protiva, Collect. Czech. Chem. Commun. 24, 3966 (1959); M. Protiva, L. Novak, DE 1240877 (1967 to SPOFA), C.A. 67, 73338j (1967).
Properties: bp0.3 135-140°. bp1 163-170°.
Boiling point: bp0.3 135-140°; bp1 163-170°
Derivative Type: Hydrochloride
CAS Registry Number: 13977-28-1
Additional Names: Mebrophenhydramine
Trademarks: Bromadryl (Spofa); Mebryl
Molecular Formula: C18H22BrNO.HCl
Molecular Weight: 384.74
Percent Composition: C 56.19%, H 6.03%, Br 20.77%, N 3.64%, O 4.16%, Cl 9.21%
Properties: Crystals from acetone + ether, mp 150-152°. LD50 in mice (mg/kg): 80 i.v.; 330 orally (Protiva, Novak).
Melting point: mp 150-152°
Toxicity data: LD50 in mice (mg/kg): 80 i.v.; 330 orally (Protiva, Novak)
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic; Aminoalkylethers.

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