Structural Formula Vector Image
Title: Dimethisoquin
CAS Registry Number: 86-80-6
CAS Name: 2-[(3-Butyl-1-isoquinolinyl)oxy]-N,N-dimethylethanamine
Additional Names: 3-butyl-1-[2-(dimethylamino)ethoxy]isoquinoline; 1-(b-dimethylaminoethoxy)-3-n-butylisoquinoline; quinisocaine
Molecular Formula: C17H24N2O
Molecular Weight: 272.39
Percent Composition: C 74.96%, H 8.88%, N 10.28%, O 5.87%
Literature References: Prepn: Wilson et al., J. Am. Chem. Soc. 71, 937 (1949); Anderson et al., J. Am. Pharm. Assoc. Sci. Ed. 41, 643 (1952); Ullyot, US 2612503 (1952 to SK & F). Clinical studies: Robinson: South. Med. J. 50, 367 (1957). Toxicity study: Fellows, Macko, J. Pharmacol. Exp. Ther. 103, 306 (1951).
Properties: Liquid, bp3 155-157°. nD20 1.5486.
Boiling point: bp3 155-157°
Index of refraction: nD20 1.5486
Derivative Type: Hydrochloride
CAS Registry Number: 2773-92-4
Trademarks: Haenal (Strathmann); Isochinol (Schwarzhaupt)
Molecular Formula: C17H24N2O.HCl
Molecular Weight: 308.85
Percent Composition: C 66.11%, H 8.16%, N 9.07%, O 5.18%, Cl 11.48%
Properties: Crystals, sol in water, alcohol, chloroform. Practically insol in ether. pH of 1% aq soln: ~4.2. LD50 i.p. in rats: 45-50 mg/kg (Fellows, Macko).
Toxicity data: LD50 i.p. in rats: 45-50 mg/kg (Fellows, Macko)
Therap-Cat: Anesthetic (topical).
Therap-Cat-Vet: Anesthetic (topical).
Keywords: Anesthetic (Local).

Other Monographs:
CarvacrolCephalinsSynhexylEnfenamic Acid
Prelog-Djerassi LactoneFluprostenolHydroflumethiazideCyclooctyne
Sodium FluorideVinylbitalAllopregnane-3α,20α-diolN-Phenylanthranilic Acid
Stannous OxideLimoninQuin2Triptorelin
©2006-2023 DrugFuture->Chemical Index Database