Dimethindene
Structural Formula Vector Image
Title: Dimethindene
CAS Registry Number: 5636-83-9
CAS Name: N,N-Dimethyl-3-[1-(2-pyridinyl)ethyl]-1H-indene-2-ethanamine
Additional Names: 2-[1-[2-[2-(dimethylamino)ethyl]inden-3-yl]ethyl]pyridine; 3-[a-(2¢-pyridyl)ethyl]-2-(b-dimethylaminoethyl)indene; dimethpyrindene
Molecular Formula: C20H24N2
Molecular Weight: 292.42
Percent Composition: C 82.15%, H 8.27%, N 9.58%
Literature References: Synthesis: Huebner et al., J. Am. Chem. Soc. 82, 2077 (1960); Huebner, US 2970149 (1961 to Ciba). Pharmacology: W. E. Barrett et al., Toxicol. Appl. Pharmacol. 3, 534 (1961).
 
Derivative Type: Maleate
CAS Registry Number: 3614-69-5
Trademarks: Fenistil (Novartis)
Molecular Formula: C20H24N2.C4H4O4
Molecular Weight: 408.49
Percent Composition: C 70.57%, H 6.91%, N 6.86%, O 15.67%
Properties: Crystals, mp 159-161°. LD50 in rats (mg/kg): 26.8 i.v.; 618.2 orally (Barrett).
Melting point: mp 159-161°
Toxicity data: LD50 in rats (mg/kg): 26.8 i.v.; 618.2 orally (Barrett)
 
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic; Alkylamine Derivatives.

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