Structural Formula Vector Image
Title: Diaveridine
CAS Registry Number: 5355-16-8
CAS Name: 5-[(3,4-Dimethoxyphenyl)methyl]-2,4-pyrimidinediamine
Additional Names: 2,4-diamino-5-veratrylpyrimidine; 2,4-diamino-5-(3¢,4¢-dimethoxybenzyl)pyrimidine
Molecular Formula: C13H16N4O2
Molecular Weight: 260.29
Percent Composition: C 59.99%, H 6.20%, N 21.52%, O 12.29%
Literature References: Prepn: Falco et al., J. Am. Chem. Soc. 73, 3758 (1951). Hitchings, Falco, US 2624732 (1953 to Burroughs Wellcome); Stenbuck et al., J. Org. Chem. 28, 1983 (1963); Hoffer, US 3341541 (1967 to Hoffmann-La Roche); M. Hoffer et al., J. Med. Chem. 14, 462 (1971). Crystal structure: T. F. Koetzle, G. Williams, Acta Crystallogr. B34, 323 (1978).
Properties: Crystals, mp 233°.
Melting point: mp 233°
NOTE: Ingredient of Darvisul (Burroughs Wellcome) which also contains sulfaquinoxaline.
Therap-Cat-Vet: Antiprotozoan (in combination with sulfaquinoxaline).

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