Structural Formula Vector Image
Title: Cyclooctyne
CAS Registry Number: 1781-78-8
Molecular Formula: C8H12
Molecular Weight: 108.18
Percent Composition: C 88.82%, H 11.18%
Literature References: Highly strained, highly reactive cycloalkyne. Prepn: A. T. Blomquist, L. H. Liu, J. Am. Chem. Soc. 75, 2153 (1953); G. Wittig, A. Krebs, Ber. 94, 3260 (1961). Improved synthesis: L. Brandsma, H. D. Verkruijsse, Synthesis 1978, 290. Molecular structure: M. Traetteberg et al., J. Mol. Struct. 128, 217 (1985). Review of synthetic applications: D. Heber et al., Eur. J. Org. Chem. 2005, 4231-4247.
Properties: bp740 157.5-158°. bp20 50-55°. mp -34° to-32°. nD20 1.4876. d420 0.868.
Melting point: mp -34° to-32°
Boiling point: bp740 157.5-158°; bp20 50-55°
Index of refraction: nD20 1.4876
Density: d420 0.868
Use: Building block in cycloaddition reactions.

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