Structural Formula Vector Image
Title: Chlorodibromomethane
CAS Registry Number: 124-48-1
CAS Name: Dibromochloromethane
Additional Names: chlorobromoform; monochlorodibromomethane; DBCM
Manufacturers' Codes: NCI-C55254
Molecular Formula: CHBr2Cl
Molecular Weight: 208.28
Percent Composition: C 5.77%, H 0.48%, Br 76.73%, Cl 17.02%
Literature References: Trihalomethane contaminant found in chlorinated water. Prepn: O. Jacobsen, R. Neumeister, Ber. 15, 599 (1882); M. Fedorynski et al., Synth. Commun. 7, 287 (1977). Toxicity studies: F. J. Bowman et al., Toxicol. Appl. Pharmacol. 44, 213 (1978); Y. Aida et al., J. Toxicol. Sci. 17, 119 (1992). Review of toxicology and human exposure: Toxicological Profile for Bromoform and Dibromochloromethane (PB2006-100001, 2005) 273 pp. Review of carcinogenic risk: IARC Monographs 52, 243-268 (1991).
Properties: Liquid. bp 121.3-121.8° (Fedorynski); also reported as bp 123-125° (Jacobsen). d15 2.4450. nD20 1.5471. Sol in ethanol, ether, acetone. LD50 in male, female rats (mg/kg): 370, 760 orally (Aida); in male, female mice (mg/kg): 800, 1200 by gavage (Bowman).
Boiling point: bp 121.3-121.8° (Fedorynski); bp 123-125° (Jacobsen)
Index of refraction: nD20 1.5471
Density: d15 2.4450
Toxicity data: LD50 in male, female rats (mg/kg): 370, 760 orally (Aida); in male, female mice (mg/kg): 800, 1200 by gavage (Bowman)
Use: Chemical reagent/intermediate in organic synthesis.

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