Structural Formula Vector Image
Title: Azanidazole
CAS Registry Number: 62973-76-6
CAS Name: (E)-4-[2-(1-Methyl-5-nitro-1H-imidazol-2-yl)ethenyl]-2-pyrimidinamine
Additional Names: (E)-2-amino-4-[2-(1-methyl-5-nitroimidazol-2-yl)vinyl]pyrimidine; nitromidine
Manufacturers' Codes: F-4
Trademarks: Triclose (ICT)
Molecular Formula: C10H10N6O2
Molecular Weight: 246.23
Percent Composition: C 48.78%, H 4.09%, N 34.13%, O 13.00%
Literature References: Prepn and use: A. Garzia, DE 2358483; eidem, US 3882105; US 3969520 (1974, 1975, 1976 all to Chemoterapico). Toxicological and teratological studies: R. Tammiso et al., Arzneim.-Forsch. 28, 2251 (1978).
Properties: Bright yellow odorless powder, mp 232-235°. Sol in DMF, DMSO, mineral oils and acids. Slightly sol in dioxane and acetone. LD50 in mice, rats (mg/kg): 5100, 7600 orally; 590, 860 i.p. (Tammiso).
Melting point: mp 232-235°
Toxicity data: LD50 in mice, rats (mg/kg): 5100, 7600 orally; 590, 860 i.p. (Tammiso)
Therap-Cat: Antiprotozoal (Trichomonas).
Keywords: Antiprotozoal (Trichomonas).

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