Structural Formula Vector Image
Title: Apicycline
CAS Registry Number: 15599-51-6
CAS Name: a-[4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamido]-4-(2-hydroxyethyl)-1-piperazineacetic acid
Additional Names: N-[(2-hydroxyethyl)piperazinocarboxymethyl]tetracycline
Manufacturers' Codes: RIT-1140
Molecular Formula: C30H38N4O11
Molecular Weight: 630.64
Percent Composition: C 57.14%, H 6.07%, N 8.88%, O 27.91%
Literature References: Semi-synthetic antibiotic similar to tetracycline. Prepn: Rondelet, NL 6515688 C.A. 66, 46260a (1967) and BE 673130 C.A. 68, 104840u (1968) (both 1966 to Recherche & Ind. Ther.); Valcavi et al., Farmaco Ed. Sci. 21, 775 (1966); Rondelet, Froment, Ann. Pharm. Fr. 26, 63 (1968).
Properties: Yellow, amorphous powder with slight amine odor, mp 144.5° (dec). Freely sol in water. [a]D -123° (c = 0.5 in methanol); [a]D -133° (c = 0.5 in water).
Melting point: mp 144.5° (dec)
Optical Rotation: [a]D -123° (c = 0.5 in methanol); [a]D -133° (c = 0.5 in water)
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); Tetracyclines.
Status: This monograph has been retired and is no longer subject to revision or update.

Other Monographs:
Silver(II) OxideMDMARokitamycinTetraethyl Pyrophosphate
n-Propyl NitrateCreosote, Coal TarRose BengalTrofosfamide
Methyl N-MethylnipecotateL-2-Oxo-4-thiazolidinecarboxylic acidFlumequine1,5-Pentanediol
Sodium HypochloriteAmmonium Boratep-DimethylaminobenzalrhodanineTolpovidone 131I
©2006-2020 DrugFuture->Chemical Index Database