Structural Formula Vector Image
Title: Aminoacetophenone
Molecular Formula: C8H9NO
Molecular Weight: 135.16
Percent Composition: C 71.09%, H 6.71%, N 10.36%, O 11.84%
Literature References: Prepn of m-, o-, and p-isomers: Grammaticakis, Compt. Rend. 235, 546 (1952); Braude et al., J. Chem. Soc. 1954, 3586. Prepn of m-isomer: Tinsley, US 2797244 (1957 to Union Carbide); of p-isomer: Norman et al., Can. J. Chem. 40, 1547 (1962). Toxicity studies: J. M. Vandenbelt et al., J. Pharmacol. Exp. Ther. 80, 31 (1944); H. F. Smyth et al., Arch. Ind. Hyg. Occup. Med. 10, 61 (1954).
Derivative Type: m-Aminoacetophenone
Additional Names: 1-(3-Aminophenyl)ethanone; 3¢-aminoacetophenone; m-aminoacetylbenzene
Properties: Yellow leaflets, mp 98-99°. Partly volatile in steam. LD50 orally in rats: 1.87 g/kg (Smyth).
Melting point: mp 98-99°
Toxicity data: LD50 orally in rats: 1.87 g/kg (Smyth)
Derivative Type: o-Aminoacetophenone
Properties: Yellow oily liquid. bp760 250-252° (some dec); bp17 135°. Volatile with steam. Practically insol in water. Sol in alc.
Boiling point: bp760 250-252° (some dec); bp17 135°
Derivative Type: p-Aminoacetophenone
Properties: Yellow needles, pleasant, characteristic odor. mp 106°. bp 293-295°. Sparingly sol in cold, freely in hot water; sol in alc, ether, HCl; sparingly sol in benzene. LD50 i.p. in rats: 260 mg/kg (Vandenbelt).
Melting point: mp 106°
Boiling point: bp 293-295°
Toxicity data: LD50 i.p. in rats: 260 mg/kg (Vandenbelt)

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