Acetyl Chloride
Structural Formula Vector Image
Title: Acetyl Chloride
CAS Registry Number: 75-36-5
Molecular Formula: C2H3ClO
Molecular Weight: 78.50
Percent Composition: C 30.60%, H 3.85%, Cl 45.16%, O 20.38%
Line Formula: CH3COCl
Literature References: Prepd from acetic acid and chlorine in the presence of phosphorus; from acetic acid and salts of chlorosulfonic acid; from sodium acetate and sulfuryl chloride. Details of prepn: Gattermann-Wieland, Praxis des Organischen Chemikers (de Gruyter, Berlin, 40th ed., 1961) p 111; A. I. Vogel, Practical Organic Chemistry (Longmans, London, 3rd ed., 1959) p 367. Lab prepn from acetic anhydride and calcium chloride: Gmünder, Helv. Chim. Acta 36, 2021 (1953).
Properties: Flammable liquid; pungent odor. Extremely irritating to the eyes. Imparts a green tinge to a colorless flame. d 1.104. mp -112°. bp 52°. nD20 1.3898. Decomposed violently by water or alc. Miscible with benzene, chloroform, ether, glacial acetic acid, petr ether. Protect from water.
Melting point: mp -112°
Boiling point: bp 52°
Index of refraction: nD20 1.3898
Density: d 1.104
CAUTION: Irritant, corrosive. Causes severe burns. Avoid contact with skin, eyes, mucous membranes.
Use: Acetylating agent; in testing for cholesterol, determination of H2O in organic liquids.

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