2-Aminobenzothiazole
Structural Formula Vector Image
Title: 2-Aminobenzothiazole
CAS Registry Number: 136-95-8
CAS Name: 2-Benzothiazolamine
Molecular Formula: C7H6N2S
Molecular Weight: 150.20
Percent Composition: C 55.98%, H 4.03%, N 18.65%, S 21.35%
Literature References: Prepd from 2-chlorobenzothiazole by treatment with alcoholic ammonia at 150-160°: Hofmann, Ber. 12, 1129 (1880); 13, 11 (1881); from benzothiazole by boiling with hydroxylamine in water or in 2N NaOH: Skraup, Ann. 419, 65 (1919). Toxicity study: E. F. Domino et al., J. Pharmacol. Exp. Ther. 105, 486 (1952).
Properties: Leaflets from water, mp 132°. Distills without decompn. Very sparingly sol in water; freely in alcohol, ether, chloroform; sol in concd acids. LD50 i.v. in mice: 126 mg/kg (Domino).
Melting point: mp 132°
Toxicity data: LD50 i.v. in mice: 126 mg/kg (Domino)
Use: In the prepn of azo dyes.

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