16-Epiestriol
Structural Formula Vector Image
Title: 16-Epiestriol
CAS Registry Number: 547-81-9
CAS Name: (16b,17b)-Estra-1,3,5(10)-triene-3,16,17-triol
Additional Names: D1,3,5-estratriene-3,16b,17b-triol; 16-epioestriol
Trademarks: Actriol (Organon)
Molecular Formula: C18H24O3
Molecular Weight: 288.38
Percent Composition: C 74.97%, H 8.39%, O 16.64%
Literature References: Isoln from urine of pregnant women: Marrian, Bauld, Biochem. J. 59, 136 (1955); Watson, Marrian, ibid. 63, 64 (1956). From human placenta: Diczfalusy, Halla, Acta Endocrinol. 27, 303 (1958). Prepn by reduction of 3,16b-diacetoxy-1,3,5(10)-estratrien-17-one: Biggerstaff, Gallagher, J. Org. Chem. 22, 1220 (1957).
Properties: Crystals from methanol + benzene, mp 289-291°. [a]D15 +76° (c = 0.297 in ethanol).
Melting point: mp 289-291°
Optical Rotation: [a]D15 +76° (c = 0.297 in ethanol)
 
Derivative Type: Epiestriol-3-allyl ether
Literature References: Prepn: Huffman, US 3002009 (1961 to Lasdon Found).
Properties: Crystals, mp 156-156.5°.
Melting point: mp 156-156.5°

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