Licorice Fluidextract
Prepare Licorice Fluidextract as follows (see Pharmaceutical Compounding—Nonsterile Preparations 795). To 1000 g of coarsely ground Licorice, add about 3000 mL of boiling Purified Water, mix, and allow to macerate in a suitable, covered percolator for 2 h. Allow the percolation to proceed at a rate of 1–3 mL/min, gradually adding boiling Purified Water until the Licorice is exhausted. Add enough diluted ammonia solution to the percolate to impart a distinctly ammoniacal odor, and boil the liquid actively under normal atmospheric pressure until it is reduced in volume to about 1500 mL. Filter the liquid, evaporate the filtrate on a steam bath until the residue measures 750 mL, cool, gradually add 250 mL of Alcohol and enough Purified Water to make the product measure 1000 mL, and mix.
•  Alcohol Content, Method I 611: 20.0%–24.0%
•  Packaging and Storage: Preserve in tight, light-resistant containers, and avoid exposure to direct sunlight and to excessive heat.
•  Labeling: The label states the Latin binomial and, following the official name, the part of the plant source from which the article was derived.
Auxiliary Information— Please check for your question in the FAQs before contacting USP.
Topic/QuestionContactExpert Committee
MonographMaged H. Sharaf, Ph.D.
Principal Scientific Liaison
(DS2010) Monographs - Dietary Supplements
USP35–NF30 Page 1843
Pharmacopeial Forum: Volume No. 27(4) Page 2799