Vanilla Tincture
» Prepare Vanilla Tincture as follows (see Pharmaceutical Compounding—Nonsterile Preparations 795):
Vanilla, cut into small pieces 100 g
Purified Water 200 mL
Alcohol 207 mL
Sucrose, in coarse granules 200 g
Diluted Alcohol, a sufficient quantity to make 1000 mL
Add Purified Water to the comminuted Vanilla in a suitable covered container, and macerate for 12 hours, preferably in a warm place. Add Alcohol to the mixture, mix, and macerate for about 3 days. Transfer the mixture to a percolator containing Sucrose, and drain. Pack the drug firmly, and percolate slowly, using Diluted Alcohol as the menstruum.
Packaging and storage— Preserve in tight, light-resistant containers, and avoid exposure to direct sunlight and excessive heat.
Labeling— The label states the Latin binomial name and, following the official name, the part of the plant source from which the article was derived.
Alcohol content, Method I 611: between 38.0% and 42.0% of C2H5OH.
Auxiliary Information— Please check for your question in the FAQs before contacting USP.
Topic/Question Contact Expert Committee
Monograph Jeanne H. Sun
Assistant Scientific Liaison
(CMP2010) Compounding
USP35–NF30 Page 2012
Pharmacopeial Forum: Volume No. 27(4) Page 2805