(trye as' e tin).
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C9H14O6 218.21

1,2,3-Propanetriol triacetate.
Glyceryl triacetate [102-76-1].
» Triacetin contains not less than 97.0 percent and not more than 100.5 percent of C9H14O6, calculated on the anhydrous basis.
Packaging and storage— Preserve in tight containers.
USP Reference standards 11
USP Triacetin RS Click to View Structure
B: The solution prepared as directed in the Assay responds to the tests for Acetate 191.
Specific gravity 841: not less than 1.152 and not more than 1.158.
Refractive index 831: not less than 1.429 and not more than 1.430.
Acidity— Dilute 25 g of Triacetin, accurately weighed, with 50 mL of neutralized alcohol, add 5 drops of phenolphthalein TS, and titrate with 0.020 N sodium hydroxide: not more than 1.0 mL of 0.020 N sodium hydroxide is required for neutralization.
Water, Method I 921: not more than 0.2% is found.
Assay— Transfer about 1 g of Triacetin, accurately weighed, to a 250-mL boiling flask, add 50.0 mL of 0.5 N alcoholic potassium hydroxide VS, connect the flask to a water-jacketed condenser, and reflux on a steam bath for 45 minutes, swirling frequently. Cool, add 5 drops of phenolphthalein TS, and titrate the excess alkali with 0.5 N hydrochloric acid VS. Perform a blank determination (see Residual Titrations under Titrimetry 541). Each mL of 0.5 N alcoholic potassium hydroxide is equivalent to 36.37 mg of C9H14O6.
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Topic/Question Contact Expert Committee
Monograph Leonel M. Santos, Ph.D.
Senior Scientific Liaison
(SM12010) Monographs - Small Molecules 1
Reference Standards RS Technical Services
USP35–NF30 Page 4922