Suspension Structured Vehicle
» Prepare Suspension Structured Vehicle as follows (see Pharmaceutical Compounding—Nonsterile Preparations 795):
Potassium Sorbate 0.15 g
Xanthan Gum 0.15 g
Citric Acid, Anhydrous 0.15 g
Sucrose 20 g
Purified Water, a sufficient quantity to make 100 mL
Transfer the Potassium Sorbate to a suitable beaker, and dissolve in 50 mL of Purified Water. Place the beaker on an electric hot plate and stirrer, and add into the vortex, slowly stirring, the Xanthan Gum. Apply minimal heat, and incorporate the Citric Acid and the Sucrose. Add a sufficient quantity of Purified Water to obtain a final volume of 100 mL, and mix.
Packaging and storage— Preserve in tight, light-resistant containers. Store at room temperature, and avoid freezing.
Labeling— Label it to state that it must be well shaken before using.
Beyond-use date— Thirty days after the day on which it was compounded.
Auxiliary Information— Please check for your question in the FAQs before contacting USP.
Topic/Question Contact Expert Committee
Monograph Jeanne H. Sun
Assistant Scientific Liaison
1-301-816-3361
(CMP2010) Compounding
USP35–NF30 Page 2002
Pharmacopeial Forum: Volume No. 28(2) Page 429