Sorbic Acid
C6H8O2 112.13
2,4-Hexadienoic acid, (E,E)-; 2,4-Hexadienoic acid;
(E,E)-Sorbic acid; Sorbic acid
[110-44-1].
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C6H8O2 112.13
2,4-Hexadienoic acid, (E,E)-; 2,4-Hexadienoic acid;
(E,E)-Sorbic acid; Sorbic acid
[110-44-1].DEFINITION
Sorbic Acid contains NLT 99.0% and NMT 101.0% of C6H8O2, calculated on the anhydrous basis.
IDENTIFICATION
• B.
A 1-in-400,000 solution in isopropyl alcohol exhibits an absorbance maximum at 254 ± 2 nm.
ASSAY
• Procedure
Sample solution:
Dissolve 250 mg of Sorbic Acid in a mixture of 50 mL of methanol and 25 mL of water that previously has been neutralized with 0.02 N sodium hydroxide. Add phenolphthalein TS.
Analysis:
Titrate with 0.1 N sodium hydroxide VS to the first pink color that persists for at least 30 s. Each mL of 0.1 N sodium hydroxide is equivalent to 11.21 mg of C6H8O2.
Acceptance criteria:
99.0%–101.0% on the anhydrous basis
IMPURITIES
SPECIFIC TESTS
• Melting Range or Temperature 
741
:
132
–135
741:
132–135
• Water Determination, Method I 921:
NMT 0.5%
921:
NMT 0.5%
ADDITIONAL REQUIREMENTS
• Packaging and Storage:
Preserve in tight containers, protected from light, and avoid exposure to excessive heat.
• USP Reference Standards 11
11
USP Sorbic Acid RS
Auxiliary Information—
Please check for your question in the FAQs before contacting USP.
| Topic/Question | Contact | Expert Committee |
|---|---|---|
| Monograph | Robert H. Lafaver, M.S.
Scientific Liaison 1-301-816-8335 |
(EXC2010) Monographs - Excipients |
| Reference Standards | RS Technical Services 1-301-816-8129 rstech@usp.org |
USP35–NF30 Page 1963
Pharmacopeial Forum: Volume No. 36(4) Page 951