Senna Fluidextract
Prepare Senna Fluidextract as follows. Mix 1000 g of Senna, in coarse powder, with a sufficient quantity (600–800 mL) of menstruum consisting of a mixture of 1 volume of alcohol and 2 volumes of water to make it evenly and distinctly damp. After 15 min, pack the mixture firmly into a suitable percolator, and cover the drug with additional menstruum. Macerate for 24 h, then percolate at a moderate rate, adding fresh menstruum, until the drug is practically exhausted of its active principals. Reserve the first 800 mL of percolate, and use it to dissolve the residue from the additional percolate that has been concentrated to a soft extract at a temperature not to exceed 60. Add water and alcohol to make the product measure 1000 mL.
•  Alcohol Determination, Method I 611: 23.0%–27.0% of C2H5OH
•  Packaging and Storage: Preserve in tight, light-resistant containers, and avoid exposure to direct sunlight and to excessive heat.
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Topic/Question Contact Expert Committee
Monograph Maged H. Sharaf, Ph.D.
Principal Scientific Liaison
(DS2010) Monographs - Dietary Supplements
USP35–NF30 Page 4626