Polyoxyl 35 Castor Oil
(pol'' ee ox' il kas' tor oyl).
» Polyoxyl 35 Castor Oil contains mainly the tri-ricinoleate ester of ethoxylated glycerol, with smaller amounts of polyethylene glycol ricinoleate and the corresponding free glycols. It results from the reaction of glycerol ricinoleate with about 35 moles of ethylene oxide.
Packaging and storage—
Preserve in tight containers.
USP Reference standards 
11
—
11—
USP Polyoxyl 35 Castor Oil RS
Identification—
B:
Dissolve about 0.1 g in 10 mL of alcoholic potassium hydroxide TS, boil for about 3 minutes, and evaporate to dryness. Mix the residue with 5 mL of water: it dissolves, yielding a clear solution. Add a few drops of glacial acetic acid: a white precipitate is formed.
C:
To a solution (1 in 20) add bromine TS, dropwise: the bromine is decolorized.
Specific gravity 841:
between 1.05 and 1.06.
841:
between 1.05 and 1.06.
Viscosity 911:
between 600 and 850 centipoises at 25
, a capillary viscometer being used.
911:
between 600 and 850 centipoises at 25, a capillary viscometer being used.
Acid value 401:
not more than 2.0.
401:
not more than 2.0.
Hydroxyl value 401:
between 65 and 80.
401:
between 65 and 80.
Iodine value 401:
between 25 and 35.
401:
between 25 and 35.
Saponification value 401:
between 60 and 75.
401:
between 60 and 75.
Water, Method I 921:
not more than 3.0%.
921:
not more than 3.0%.
Residue on ignition 281:
not more than 0.3%.
281:
not more than 0.3%.
Heavy metals, Method II 231:
0.001%.
231:
0.001%.
Auxiliary Information—
Please check for your question in the FAQs before contacting USP.
| Topic/Question | Contact | Expert Committee |
|---|---|---|
| Monograph | Robert H. Lafaver, M.S.
Scientific Liaison 1-301-816-8335 |
(EXC2010) Monographs - Excipients |
| Reference Standards | RS Technical Services 1-301-816-8129 rstech@usp.org |
USP35–NF30 Page 1916
Pharmacopeial Forum: Volume No. 31(6) Page 1671