Neomycin and Polymyxin B Sulfates Solution for Irrigation
» Neomycin and Polymyxin B Sulfates Solution for Irrigation is a sterile, aqueous solution containing the equivalent of not less than 90.0 percent and not more than 130.0 percent of the labeled amounts of neomycin and of polymyxin B. It may contain a suitable preservative.
Packaging and storage—
Preserve in tight containers.
Labeling—
Label it to indicate that it is to be diluted for use in a urinary bladder irrigation and is not intended for injection.
Thin-layer chromatographic identification test 
201BNP
:
meets the requirements.
201BNP:
meets the requirements.
Sterility 71—
It meets the requirements when tested as directed for Membrane Filtration under Test for Sterility of the Product to be Examined.
71—
It meets the requirements when tested as directed for Membrane Filtration under Test for Sterility of the Product to be Examined.
pH 791:
between 4.5 and 6.0.
791:
between 4.5 and 6.0.
Assay for neomycin and Assay for polymyxin B—
Proceed with Neomycin and Polymyxin B Sulfates Solution for Irrigation as directed in the Assay for neomycin and in the Assay for polymyxin B under Neomycin and Polymyxin B Sulfates and Hydrocortisone Otic Solution.
Auxiliary Information—
Please check for your question in the FAQs before contacting USP.
| Topic/Question | Contact | Expert Committee |
|---|---|---|
| Monograph | Ahalya Wise, M.S.
Senior Scientific Liaison 1-301-816-8161 |
(SM12010) Monographs - Small Molecules 1 |
| Reference Standards | RS Technical Services 1-301-816-8129 rstech@usp.org |
|
| 71 |
Radhakrishna S Tirumalai, Ph.D.
Principal Scientific Liaison 1-301-816-8339 |
(GCM2010) General Chapters - Microbiology |
USP35–NF30 Page 4020
Pharmacopeial Forum: Volume No. 28(4) Page 1159