(an' e thole).
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C10H12O 148.20
Benzene, 1-methoxy-4-(1-propenyl)-, (E)-;    
(E)-p-Propenylanisole     [4180-23-8].
Synthetic     [104-46-1].
Anethole is obtained from Anise Oil and other sources, or it is prepared synthetically.
•  Heavy Metals, Method II 231: NMT 20 ppm
•  Limit of Phenols
Sample:  1 mL
Analysis:  Shake the Sample with 20 mL of water, and allow the liquids to separate. Pass the water layer through a filter paper previously moistened with water, and to 10 mL of the filtrate add 3 drops of ferric chloride TS.
Acceptance criteria:  No purple or purplish color is produced.
•  Aldehydes and Ketones
Sample:  10 mL
Analysis:  Shake the Sample with 50 mL of a saturated solution of sodium bisulfite in a graduated cylinder, and allow the mixture to stand for 6 h.
Acceptance criteria:  No appreciable diminution in the volume of Anethole occurs, and no crystalline deposit separates.
•  Specific Gravity 841: 0.983–0.988
•  Distilling Range, Method I 721: 231–237, a correction factor of 0.063/mm being applied as necessary
•  Refractive Index 831: 1.557–1.561
•  Packaging and Storage: Preserve in tight, light-resistant containers.
•  Labeling: Label to indicate whether it is of natural sources or is prepared synthetically.
Auxiliary Information— Please check for your question in the FAQs before contacting USP.
Topic/Question Contact Expert Committee
Monograph Robert H. Lafaver, M.S.
Scientific Liaison
(EXC2010) Monographs - Excipients
USP35–NF30 Page 1700