Aminohippuric Acid
(a mee'' noe hi pure' ik as' id).
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C9H10N2O3 194.19

Glycine, N-(4-aminobenzoyl)-.
p-Aminohippuric acid [61-78-9].
» Aminohippuric Acid contains not less than 98.0 percent and not more than 100.5 percent of C9H10N2O3, calculated on the dried basis.
Packaging and storage— Preserve in tight, light-resistant containers.
USP Reference standards 11
USP Aminohippuric Acid RS Click to View Structure
B: Dissolve about 10 mg in 5 mL of water, and add 0.5 mL of 3 N hydrochloric acid, 0.5 mL of sodium nitrite solution (1 in 10), and a solution of 0.20 g of 2-naphthol in 10 mL of 6 N ammonium hydroxide: a red color is produced.
Loss on drying 731 Dry it at 105 for 2 hours: it loses not more than 0.25% of its weight.
Residue on ignition 281: not more than 0.25%.
Assay— Transfer about 150 mg, accurately weighed, of Aminohippuric Acid to a beaker or a casserole. Add 5 mL of hydrochloric acid and 50 mL of water, and proceed as directed under Nitrite Titration 451, beginning with “stir until dissolved.” Each mL of 0.1 M sodium nitrite is equivalent to 19.42 mg of C9H10N2O3.
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Monograph Thomas A. Sigambris, M.S.
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(BIO12010) Monographs - Biologics and Biotechnology 1
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USP35–NF30 Page 2171