Cascara Sagrada Fluidextract
Prepare Cascara Sagrada Fluidextract as follows. To 1000 g of coarsely ground Cascara Sagrada add 3000 mL of boiling water, and allow to macerate in a suitable percolator for 2 h. Allow the percolation to proceed at a moderate rate, gradually adding boiling water until the drug is practically exhausted of its active principles. Evaporate the percolate on a water bath or in a vacuum still to NMT 800 mL. Cool, add 200 mL of alcohol and, if necessary, add sufficient water to make the product measure 1000 mL. Mix.
•  Alcohol Determination, Method I 611: 18.0%–20.0% of C2H5OH
•  Packaging and Storage: Preserve in tight, light-resistant containers, and avoid exposure to direct sunlight and to excessive heat.
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Topic/Question Contact Expert Committee
Monograph Maged H. Sharaf, Ph.D.
Principal Scientific Liaison
(DS2010) Monographs - Dietary Supplements
USP35–NF30 Page 2522