Carbachol Intraocular Solution
» Carbachol Intraocular Solution is a sterile solution of Carbachol in an aqueous medium. It contains not less than 90.0 percent and not more than 115.0 percent of the labeled amount of C6H15ClN2O2. It contains no preservatives or antimicrobial agents.
Packaging and storage Preserve in tight containers, at controlled room temperature, and protect from freezing.
Labeling Label it to indicate that it is for single-dose intraocular use only, and that the unused portion is to be discarded.
USP Reference standards 11
Identification To 5 mL of Intraocular Solution, add 4 or 5 drops of saturated (filtered) ammonium reineckate solution: a pink precipitate is formed that is soluble in acetone; the acetone solution is red.
Sterility 71: meets the requirements.
pH 791: between 5.0 and 7.5.
Hypochlorite reagent and Standard preparationPrepare as directed in the Assay under Carbachol Ophthalmic Solution.
Assay preparation Dilute, if necessary, an accurately measured volume of Intraocular Solution quantitatively and stepwise with water to obtain a solution containing about 100 µg of carbachol per mL.
Auxiliary Information Please check for your question in the FAQs before contacting USP.
USP35NF30 Page 2480Pharmacopeial Forum: Volume No. 33(2) Page 213