Carbachol Intraocular Solution
» Carbachol Intraocular Solution is a sterile solution of Carbachol in an aqueous medium. It contains not less than 90.0 percent and not more than 115.0 percent of the labeled amount of C6H15ClN2O2. It contains no preservatives or antimicrobial agents.
Packaging and storage—
Preserve in tight containers, at controlled room temperature, and protect from freezing.
Labeling—
Label it to indicate that it is for single-dose intraocular use only, and that the unused portion is to be discarded.
USP Reference standards 
11
—
11—
USP Carbachol RS 
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Identification—
To 5 mL of Intraocular Solution, add 4 or 5 drops of saturated (filtered) ammonium reineckate solution: a pink precipitate is formed that is soluble in acetone; the acetone solution is red.
Sterility 71:
meets the requirements.
71:
meets the requirements.
pH 791:
between 5.0 and 7.5.
791:
between 5.0 and 7.5.
Assay—
Hypochlorite reagent
and Standard preparation—Prepare as directed in the Assay under Carbachol Ophthalmic Solution.
Assay preparation—
Dilute, if necessary, an accurately measured volume of Intraocular Solution quantitatively and stepwise with water to obtain a solution containing about 100 µg of carbachol per mL.
Procedure—
Proceed as directed for Procedure in the Assay under Carbachol Ophthalmic Solution.
Auxiliary Information—
Please check for your question in the FAQs before contacting USP.
| Topic/Question | Contact | Expert Committee |
|---|---|---|
| Monograph | Ravi Ravichandran, Ph.D.
Principal Scientific Liaison 1-301-816-8330 |
(SM42010) Monographs - Small Molecules 4 |
| Reference Standards | RS Technical Services 1-301-816-8129 rstech@usp.org |
|
| 71 |
Radhakrishna S Tirumalai, Ph.D.
Principal Scientific Liaison 1-301-816-8339 |
(GCM2010) General Chapters - Microbiology |
USP35–NF30 Page 2480
Pharmacopeial Forum: Volume No. 33(2) Page 213