Camphor Spirit
» Camphor Spirit is an alcohol solution containing, in each 100 mL, not less than 9.0 g and not more than 11.0 g of camphor (C10H16O).
Camphor 100 g
Alcohol, a sufficient quantity,  
to make 1000 mL
Dissolve the camphor in about 800 mL of the alcohol, and add alcohol to make 1000 mL. Filter, if necessary.
Packaging and storage— Preserve in tight containers.
Alcohol content, Method II 611: between 80.0% and 87.0% of C2H5OH, the dilution to approximately 2% alcohol being made with methanol instead of with water.
Assay— Transfer 2.0 mL of Camphor Spirit to a suitable pressure bottle containing 50 mL of freshly prepared dinitrophenylhydrazine TS. Close the pressure bottle, immerse it in a water bath, and maintain at about 75 for 16 hours. Cool to room temperature, and transfer the contents to a beaker with the aid of 100 mL of 3 N sulfuric acid. Allow to stand at room temperature for not less than 12 hours, transfer the precipitate to a tared filter crucible, and wash with 100 mL of 3 N sulfuric acid followed by 75 mL of cold water in divided portions. Continue the suction until the excess water is removed, dry the crucible and precipitate at 80 for 2 hours, cool, and weigh. The weight of the precipitate so obtained, multiplied by 0.4581, represents the weight of C10H16O in the specimen taken.
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Monograph Behnam Davani, Ph.D., M.B.A.
Senior Scientific Liaison
1-301-816-8394
(SM12010) Monographs - Small Molecules 1
USP35–NF30 Page 2468