Nabumetone: A white, or almost white, crystalline powder. Freely soluble in acetone; sparingly soluble in alcohol and in methanol; practically insoluble in water.
Nadolol: White to off-white, practically odorless, crystalline powder. Freely soluble in alcohol and in methanol; soluble in water at pH 2; slightly soluble in chloroform, in methylene chloride, in isopropyl alcohol, and in water (between pH 7 and pH 10); insoluble in acetone, in benzene, in ether, in hexane, and in trichloroethane.
Nafcillin Sodium: White to yellowish-white powder, having not more than a slight characteristic odor. Freely soluble in water and in chloroform; soluble in alcohol.
Nalidixic Acid: White to very pale yellow, odorless, crystalline powder. Soluble in chloroform, in methylene chloride, and in solutions of fixed alkali hydroxides and carbonates; slightly soluble in acetone, in alcohol, in methanol, and in toluene; very slightly soluble in ether and in water.
Naloxone Hydrochloride: White to slightly off-white powder. Its aqueous solution is acidic. Soluble in water, in dilute acids, and in strong alkali; slightly soluble in alcohol; practically insoluble in ether and in chloroform.
Naloxone Hydrochloride Injection: Clear, colorless liquid.
Nandrolone Decanoate: Fine, white to creamy white, crystalline powder. Is odorless, or may have a slight odor. Soluble in chloroform, in alcohol, in acetone, and in vegetable oils; practically insoluble in water.
Naphazoline Hydrochloride: White, crystalline powder. Is odorless and has a bitter taste. Melts at a temperature of about 255, with decomposition. Freely soluble in water and in alcohol; very slightly soluble in chloroform; practically insoluble in ether.
Naproxen: White to off-white, practically odorless, crystalline powder. Soluble in chloroform, in dehydrated alcohol, and in alcohol; sparingly soluble in ether; practically insoluble in water.
Naproxen Sodium: White to creamy crystalline powder. Soluble in water and in methanol; sparingly soluble in alcohol; very slightly soluble in acetone; and practically insoluble in chloroform and in toluene. Melts at about 255, with decomposition.
Narasin: White to off-white, crystalline powder. Melts at about 217, with decomposition. Soluble in methanol and in water.
Naratriptan Hydrochloride: White to pale yellow solid. Soluble in water.
Natamycin: Off-white to cream-colored powder, which may contain up to 3 moles of water. Soluble in glacial acetic acid and in dimethylformamide; slightly soluble in methanol; practically insoluble in water.
Nateglinide: White powder. Freely soluble in methanol and in alcohol; soluble in ether; sparingly soluble in acetonitrile and in octanol; practically insoluble in water.
Nefazodone Hydrochloride: Nonhygroscopic, white powder. Freely soluble in chloroform; soluble in propylene glycol; slightly soluble in polyethylene glycol and in water.
Neomycin Sulfate: White to slightly yellow powder, or cryodesiccated solid. Is odorless or practically so and is hygroscopic. Its solutions are dextrorotatory. Freely soluble in water; very slightly soluble in alcohol; insoluble in acetone, in chloroform, and in ether.
Netilmicin Sulfate: White to pale yellowish-white powder. Freely soluble in water; practically insoluble in dehydrated alcohol and in ether.
Nevirapine: White to off-white, odorless to nearly odorless, crystalline powder. Slightly soluble in alcohol and in methanol; practically insoluble in water. Hydrous form also slightly soluble in propylene glycol.
Niacin: White crystals or crystalline powder. Is odorless, or has a slight odor. Melts at about 235. Freely soluble in boiling water, in boiling alcohol, and in solutions of alkali hydroxides and carbonates; sparingly soluble in water; practically insoluble in ether.
Niacinamide: White, crystalline powder. Is odorless or practically so, and has a bitter taste. Its solutions are neutral to litmus. Freely soluble in water and in alcohol; soluble in glycerin.
Nifedipine: Yellow powder. Is affected by exposure to light. Freely soluble in acetone; practically insoluble in water.
Nimodipine: Light yellow or yellow, crystalline powder, affected by light. Freely soluble in ethyl acetate; sparingly soluble in alcohol; practically insoluble in water. Exhibits polymorphism.
Nitric Acid: Highly corrosive fuming liquid, having a characteristic, highly irritating odor. Stains animal tissues yellow. Boils at about 120. Specific gravity is about 1.41. NF category: Acidifying agent.
Nitrofurantoin: Lemon-yellow, odorless crystals or fine powder. Has a bitter aftertaste. Soluble in dimethylformamide; very slightly soluble in water and in alcohol.
Nitrofurazone: Lemon yellow, odorless, crystalline powder. Darkens slowly on exposure to light. Melts at about 236, with decomposition. Soluble in dimethylformamide; slightly soluble in propylene glycol and in polyethylene glycol mixtures; very slightly soluble in alcohol and in water; practically insoluble in chloroform and in ether.
Nitrofurazone Ointment: Yellow, opaque, and water-miscible, and has ointment-like consistency.
Nitrofurazone Topical Solution: Light yellow, clear, somewhat viscous liquid, having a faint characteristic odor. Miscible with water.
Nitrogen: Colorless, odorless, tasteless gas. Is nonflammable and does not support combustion. One L at 0 and at a pressure of 760 mm of mercury weighs about 1.251 g. One volume dissolves in about 65 volumes of water and in about 9 volumes of alcohol at 20 and at a pressure of 760 mm of mercury. NF category: Air displacement.
Diluted Nitroglycerin: When diluted with lactose, it is a white, odorless powder. When diluted with propylene glycol or alcohol, it is a clear, colorless, or pale yellow liquid. [Note—Undiluted nitroglycerin occurs as a white to pale yellow, thick, flammable, explosive liquid. ] Undiluted nitroglycerin is soluble in methanol, in alcohol, in carbon disulfide, in acetone, in ethyl ether, in ethyl acetate, in glacial acetic acid, in benzene, in toluene, in nitrobenzene, in phenol, in chloroform, and in methylene chloride; slightly soluble in water.
Nitromersol: Brownish yellow to yellow granules or brownish yellow to yellow powder. Is odorless and tasteless and is affected by light. Soluble in solutions of alkalies and of ammonia by opening of the anhydride ring and the formation of a salt; very slightly soluble in water, in alcohol, in acetone, and in ether.
Nitromersol Topical Solution: Clear, reddish-orange solution. Is affected by light.
Nitrous Oxide: Colorless gas, without appreciable odor or taste. One L at 0 and at a pressure of 760 mm of mercury weighs about 1.97 g. One volume dissolves in about 1.4 volumes of water at 20 and at a pressure of 760 mm of mercury. Freely soluble in alcohol; soluble in ether and in oils.
Nizatidine: Off-white to buff crystalline solid. Freely soluble in chloroform; soluble in methanol; sparingly soluble in water.
Nonoxynol 9: Clear, colorless to light yellow, viscous liquid. Soluble in water, in alcohol, and in corn oil. NF category: Wetting and/or solubilizing agent.
Norepinephrine Bitartrate: White or faintly gray, odorless, crystalline powder. Slowly darkens on exposure to air and light. Its solutions are acid to litmus, having a pH of about 3.5. Freely soluble in water; slightly soluble in alcohol; practically insoluble in chloroform and in ether. Melts between 98 and 104, without previous drying of the specimen, the melt being turbid.
Norepinephrine Bitartrate Injection: Colorless or practically colorless liquid, gradually turning dark on exposure to air and light.
Norethindrone: White to creamy white, odorless, crystalline powder. Is stable in air. Soluble in chloroform and in dioxane; sparingly soluble in alcohol; slightly soluble in ether; practically insoluble in water.
Norethindrone Acetate: White to creamy white, odorless, crystalline powder. Very soluble in chloroform; freely soluble in dioxane; soluble in ether and in alcohol; practically insoluble in water.
Norfloxacin: White to pale yellow, crystalline powder. Sensitive to light and moisture. Freely soluble in acetic acid; sparingly soluble in chloroform; slightly soluble in acetone, in water, and in alcohol; very slightly soluble in methanol and in ethyl acetate; insoluble in ether.
Norgestimate: White to pale yellow powder. Very to freely soluble in methylene chloride; sparingly soluble in acetonitrile; insoluble in water.
Norgestrel: White or practically white, practically odorless, crystalline powder. Freely soluble in chloroform; sparingly soluble in alcohol; insoluble in water.
Nortriptyline Hydrochloride: White to off-white powder, having a slight, characteristic odor. Its solution (1 in 100) has a pH of about 5. Soluble in water and in chloroform; sparingly soluble in methanol; practically insoluble in ether, in benzene, and in most other organic solvents.
Noscapine: Fine, white or practically white, crystalline powder. Freely soluble in chloroform; soluble in acetone; slightly soluble in alcohol and in ether; practically insoluble in water.
Novobiocin Calcium: White or yellowish-white, odorless, crystalline powder. Freely soluble in alcohol and in methanol; sparingly soluble in acetone and in butyl acetate; slightly soluble in water and in ether; very slightly soluble in chloroform.
Novobiocin Sodium: White or yellowish-white, odorless, hygroscopic, crystalline powder. Freely soluble in water, in alcohol, in methanol, in glycerin, and in propylene glycol; slightly soluble in butyl acetate; practically insoluble in acetone, in chloroform, and in ether.
Nystatin: Yellow to light tan powder, having an odor suggestive of cereals. Is hygroscopic, and is affected by long exposure to light, heat, and air. Freely soluble in dimethylformamide and in dimethyl sulfoxide; sparingly to slightly soluble in methanol, in n-propyl alcohol, and in n-butyl alcohol; practically insoluble in water and in alcohol; insoluble in chloroform and in ether.