Notice and Warning

This product, USP32–NF27, is current from May 1, 2009 through April 30, 2010, as described below.

SIX-MONTH IMPLEMENTATION GUIDELINE

The United States Pharmacopeia–National Formulary and its Supplements become official six months after being released to the public. The USP–NF, which is released on November 1 of each year, becomes official on May 1 of the following year.

This change was adopted to give users more time to bring their methods and procedures into compliance with new and revised USP–NF requirements.

The table below describes the new official dates. The 2008 USP31–NF26, and the Supplements and Interim Revision Announcements (IRAs) to that edition, will be official until May 1, 2009, at which time the USP32–NF27 becomes official.

Publication	Release Date	Official Date	Official Until
USP32–NF27	Nov. 1, 2008	May 1, 2009	May 1, 2010 (except as superceded by Supplements, IRAs, and Revision Bulletins)
First Supplement	Feb. 1, 2009	Aug. 1, 2009	May 1, 2010 (except as superceded by Second Supplement, IRAs, and Revision Bulletins)
Second Supplement	June 1, 2009	Dec. 1, 2009	May 1, 2010 (except as superceded by IRAs and Revision Bulletins)
USP33–NF28	Nov. 1, 2009	May 1, 2010	May 1, 2011 (except as superceded by Supplements, IRAs, and Revision Bulletins)

IRAs will continue to become official on the first day of the second month of the Pharmacopeial Forum (PF) issue in which they are published as final. For instance, IRAs published as final in the May-June PF (issue 3) will become official on June 1. This table gives the details of the IRAs that will apply to USP31–NF26 and USP32–NF27.

IRA*	Release Date	Official Date	Revises
Jan. 1, 2009 IRA, PF 35(1)	Jan. 1, 2009	Feb. 1, 2009	USP31–NF26 and its Supplements
Mar. 1, 2009 IRA, PF 35(2)	Mar. 1, 2009	April 1, 2009	USP31–NF26 and its Supplements
May 1, 2009 IRA, PF 35(3)	May 1, 2009	June 1, 2009	USP32–NF27
July 1, 2009 IRA, PF 35(4)	July 1, 2009	Aug. 1, 2009	USP32–NF27 and First Supplement
Sept. 1, 2009 IRA, PF 35(5)	Sept. 1, 2009	Oct. 1, 2009	USP32–NF27 and First Supplement
Nov. 1, 2009 IRA, PF 35(6)	Nov. 1, 2009	Dec. 1, 2009	USP32–NF27 and its Supplements
Jan. 1, 2010 IRA, PF 36(1)	Jan. 1, 2010	Feb. 1, 2010	USP32–NF27 and its Supplements
Mar. 1, 2010 IRA, PF 36(2)	Mar. 1, 2010	April 1, 2010	USP32–NF27 and its Supplements

*NOTE—Beginning January 1, 2007, USP ceased identifying IRAs numerically (First, Second, etc.) and instead now designates them by the date on which they are published.

Revision Bulletins published on the USP website will continue to become official immediately upon publication, unless the Revision Bulletin specifies otherwise.

Revisions that contain a specific official date shall continue to become official upon such specified date, which supercedes the general official date for the publication.

For more information about the change in official dates, please visit the USP website at http://www.usp.org.

NOTICE AND WARNING

Concerning U.S. Patent or Trademark Rights—The inclusion in The United States Pharmacopeia or in the National Formulary of a monograph on any drug in respect to which patent or trademark rights may exist shall not be deemed, and is not intended as, a grant of, or authority to exercise, any right or privilege protected by such patent or trademark. All such rights and privileges are vested in the patent or trademark owner, and no other person may exercise the same without express permission, authority, or license secured from such patent or trademark owner.

Concerning Use of USP or NF Text—Attention is called to the fact that USP and NF text is fully copyrighted. Authors and others wishing to use portions of the text should request permission to do so from the Secretary of the USPC Board of Trustees.

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ISSN: 1930-2932 ISBN: 1-889788-73-9