Sorbitan Sesquioleate
» Sorbitan Sesquioleate is a partial oleate ester of Sorbitol and its mono- and dianhydrides. It yields, upon saponification, not less than 74.0 percent and not more than 80.0 percent of fatty acids, and not less than 22.0 percent and not more than 28.0 percent of polyols (w/w).
Packaging and storage— Preserve in tight containers.
Identification— It responds to Identification tests A and B under Sorbitan Monooleate.
Acid value 401: not more than 14.
Hydroxyl value 401: between 182 and 220.
Iodine value 401: between 65 and 75.
Saponification value 401: between 143 and 165.
Water, Method I 921: not more than 1.0%.
Residue on ignition 281: not more than 1.4%.
Assay for fatty acids— Proceed as directed for Assay for fatty acids under Sorbitan Monooleate.
Assay for polyols— Proceed as directed for Assay for polyols under Sorbitan Monooleate.
Auxiliary Information— Please check for your question in the FAQs before contacting USP.
Topic/Question Contact Expert Committee
Monograph Robert H. Lafaver, B.A.
(EM105) Excipient Monographs 1
Reference Standards Lili Wang, Technical Services Scientist
USP32–NF27 Page 1350
Pharmacopeial Forum: Volume No. 28(6) Page 1733