2H-Pyran-2,4(3H)-dione, 3-acetyl-6-methyl-, monosodium salt [4418-26-2].
» Sodium Dehydroacetate contains not less than 98.0 percent and not more than 100.5 percent of C8H7NaO4, calculated on the anhydrous basis.
Packaging and storage Preserve in well-closed containers.
A: Dissolve about 1.5 g in 10 mL of water, add 5 mL of 3 N hydrochloric acid, collect the crystals by filtration with suction, wash with 10 mL of water, and dry at 80 for 4 hours: the crystals so obtained melt between 109 and 111 (see Melting Range or Temperature 741).
B: A solution (1 in 20) responds to the tests for Sodium 191.
Water, Method I 921: between 8.5% and 10.0%.
Heavy metals, Method II 231: 0.001%.
Assay Transfer to a 125-mL conical flask about 500 mg of Sodium Dehydroacetate, accurately weighed, dissolve it in 25 mL of glacial acetic acid containing p-naphtholbenzein TS which has been previously neutralized to a blue color, and titrate with 0.1 N perchloric acid VS to the original blue color. Each mL of 0.1 N perchloric acid is equivalent to 19.01 mg of C8H7NaO4.
Auxiliary Information Please check for your question in the FAQs before contacting USP.Chromatographic Column
USP32NF27 Page 1342
Chromatographic columns text is not derived from, and not part of, USP 32 or NF 27.