Powdered St. John's Wort
» Powdered St. John's Wort is St. John's Wort reduced to a fine or a very fine powder. It contains not less than 0.6 percent of hyperforin (C35H52O4) and not less than 0.04 percent of hypericin (C30H16O8) and pseudohypericin (C30H16O9) combined.
Packaging and storage— Store in tight containers, protected from light and moisture.
Labeling— The label states the Latin binomial and, following the official name, the parts of the plant source from which the article was derived.
USP Reference standards 11
USP Hyperoside RS
USP Rutin RS.
Botanic characteristics— Buff to greenish-brown powder with an aromatic and balsamic odor; elongated and polygonal epidermal cells with thickened and beaded anticlinal walls, some accompanied by paracytic (occasionally anomocytic) stomata; fragments of leaf and sepal with schizogenous oil and pigment glands; narrow, thin-walled, elongated epidermal cells with straight and wavy anticlinal walls from petal; narrow, lignified vessels with annular or reticulate thickening; tracheids and tracheidal vessels with lignified, pitted thickening; thick-walled lignified fibers with tapering apices and occasional oblique pits; rectangular, lignified, pitted parenchyma; fibrous layer of antheral wall; pollen grains, between 20 and 25 µm in diameter, with smooth exine.
Heavy metals 231: 0.002%.
Other requirements— It meets the requirements for Identification, Total ash, Water content, Foreign organic matter, Pesticide residues, Microbial enumeration, Content of hypericin and pseudohypericin, and Content of hyperforin tests under St. John's Wort.
Auxiliary Information— Please check for your question in the FAQs before contacting USP.
Topic/Question Contact Expert Committee
Monograph Maged H. Sharaf, Ph.D.
Senior Scientist
(DSB05) Dietary Supplements - Botanicals
Reference Standards Lili Wang, Technical Services Scientist
USP32–NF27 Page 1068