» Ascorbyl Palmitate contains not less than 95.0 percent and not more than 100.5 percent of C22H38O7, calculated on the dried basis.
Packaging and storage Preserve in tight containers, in a cool, dry place.
Identification Dissolve 1 g in 25 mL of alcohol, and add 1 mL of a 1 in 1000 solution of 2,6-dichlorophenol-indophenol sodium in alcohol: the blue color of the 2,6-dichlorophenol-indophenol sodium solution is discharged immediately.
Melting range 741: between 107 and 117.
Specific rotation 781S: between +21 and +24.
Test solution: 100 mg per mL, in methanol.
Loss on drying 731 Dry it in vacuum at 60 for 1 hour: it loses not more than 2.0% of its weight.
Residue on ignition 281: not more than 0.1%.
Heavy metals, Method II 231: 0.001%.
Assay Dissolve about 300 mg of Ascorbyl Palmitate, accurately weighed, in 50 mL of alcohol, add 30 mL of water, and immediately titrate with 0.1 N iodine VS to a yellow color that persists for not less than 30 seconds. Each mL of 0.1 N iodine is equivalent to 20.73 mg of C22H38O7.
Auxiliary Information Please check for your question in the FAQs before contacting USP.Chromatographic Column
USP32NF27 Page 1167
Chromatographic columns text is not derived from, and not part of, USP 32 or NF 27.