Oleovitamin A and D Capsules
» Oleovitamin A and D Capsules contain not less than 90.0 percent of the labeled amounts of vitamins A and D. The oil in Oleovitamin A and D Capsules conforms to the definition for Oleovitamin A and D.
Packaging and storage— Preserve in tight, light-resistant containers. Store in a dry place.
Labeling— Label the Capsules to indicate the content, in mg, of vitamin A in each capsule. The vitamin A content in each capsule may be expressed also in USP Vitamin A Units. Label the Capsules to show whether they contain ergocalciferol, cholecalciferol, or vitamin D from a natural source. Label the Capsules to indicate also the vitamin D content, in µg, in each capsule. The vitamin D content may be expressed also in USP Vitamin D Units in each capsule.
Assay for vitamin A— Transfer to a saponification flask not less than 5 Capsules, add 10 to 20 mL of water, and heat for about 10 minutes. Crush any remaining solids with the blunt end of a glass rod, and proceed as directed in the second paragraph for Procedure in the Vitamin A Assay 571, beginning with “Reflux in an all-glass apparatus.”
Assay for vitamin D— Transfer to a saponification flask not less than 5 Capsules, add 10 to 20 mL of water, and heat for about 10 minutes. Crush any remaining solids with the blunt end of a glass rod, and proceed as directed for Chemical Method under Vitamin D Assay 581. The Test Preparation used in the chromatographic procedures shall contain not more than the equivalent of 7.5 mg of vitamin A or less than 125 µg of vitamin D. If the ratio of vitamin A to vitamin D in the Test Preparation exceeds 300 to 1, proceed as directed for Biological Method under Vitamin D Assay 581.
Auxiliary Information— Please check for your question in the FAQs before contacting USP.
Topic/Question Contact Expert Committee
Monograph Curtis Phinney

1-301-816-8540		 (DSN05) Dietary Supplements - Non-Botanicals
Reference Standards Lili Wang, Technical Services Scientist
1-301-816-8129
RSTech@usp.org
USP32–NF27 Page 3132