Oleovitamin A and D
» Oleovitamin A and D is a solution of vitamin A and vitamin D in fish liver oil or in an edible vegetable oil. The vitamin D is present as ergocalciferol or cholecalciferol obtained by the activation of ergosterol or 7-dehydrocholesterol or from natural sources. Oleovitamin A and D contains not less than 90.0 percent of the labeled amounts of vitamins A and D.
Packaging and storage— Preserve in tight containers, protected from light and air, preferably under an atmosphere of an inert gas. Store in a dry place.
Labeling— Label it to indicate the content of vitamin A in mg per g. The vitamin A content may also be expressed in USP Vitamin A Units per g. Label it to show whether it contains ergocalciferol, cholecalciferol, or vitamin D from a natural source. Label it to indicate also the vitamin D content in µg per g. Its vitamin D content may be expressed also in USP Vitamin D Units per g.
Assay for vitamin A— Proceed as directed under Vitamin A Assay 571.
Assay for vitamin D— Accurately measure a portion of Oleovitamin A and D expected to contain about the equivalent of 125 to 250 µg of vitamin D, but not more than 7.5 mg of vitamin A, and proceed as directed for Chemical Method under Vitamin D Assay 581. If the assay specimen contains less than the equivalent of 2.5 µg of vitamin D per g, or if the ratio of vitamin A to vitamin D exceeds 300 to 1, proceed as directed for Biological Method under Vitamin D Assay 581.
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Topic/Question Contact Expert Committee
Monograph Curtis Phinney

1-301-816-8540		 (DSN05) Dietary Supplements - Non-Botanicals
Reference Standards Lili Wang, Technical Services Scientist
1-301-816-8129
RSTech@usp.org
USP32–NF27 Page 3132
Chromatographic Column—
Chromatographic columns text is not derived from, and not part of, USP 32 or NF 27.