Octoxynol 9
Poly(oxy-1,2-ethanediyl), -(octylphenyl)--hydroxy-. Polyethylene glycol mono(octylphenyl) ether [9002-93-1]. » Octoxynol 9 is an anhydrous liquid mixture consisting chiefly of monooctylphenyl ethers of polyethylene glycols, corresponding to the formula:
C8H17C6H4(OCH2CH2)nOH
in which the average value of n is about 9.
Packaging and storage
Preserve in tight containers.
USP Reference standards 11
USP Octoxynol 9 RS.
Identification, Infrared Absorption 197F, on undried specimen.
Cloud point
Weigh 1.00 g into a 250-mL beaker, and add 99 g of water. Dissolve completely by careful heating, while stirring at a constant slow speed with a small-propeller-blade stirrer. Center a thermometer vertically in the solution, and heat rapidly until the entire solution becomes cloudy, then raise the temperature 10. Remove the source of heat, continue stirring, and record the temperature at which the solution becomes sufficiently clear to permit seeing the entire thermometer bulb plainly: the cloud point is between 63 and 69.
Hydroxyl value 401:
between 85 and 101.
Water, Method I 921:
not more than 0.5%.
Residue on ignition 281:
not more than 0.4%.
Heavy metals 231:
0.002%.
Free ethylene oxide
Octoxynol 9 meets the requirements for Free ethylene oxide under Nonoxynol 9 (see USP monograph). In performing the test, substitute the term Octoxynol 9 for Nonoxynol 9 wherever it occurs. The limit is 5 ppm.
Limit of dioxane
It meets the requirements for Limit of dioxane under Nonoxynol 9 (see USP monograph).
Auxiliary Information
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Chromatographic Column
USP32NF27 Page 1289
Chromatographic columns text is not derived from, and not part of, USP 32 or NF 27.
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