Neomycin Sulfate and Bacitracin Zinc Ointment
» Neomycin Sulfate and Bacitracin Zinc Ointment contains the equivalent of not less than 90.0 percent and not more than 130.0 percent of the labeled amounts of neomycin and bacitracin.
Packaging and storage— Preserve in collapsible tubes or in well-closed containers.
Thin-layer chromatographic identification test 201BNP: meets the requirements.
Minimum fill 755: meets the requirements.
Water, Method I 921: not more than 0.5%, 20 mL of a mixture of toluene and methanol (7:3) being used in place of methanol in the titration vessel.
Assay for neomycin and Assay for bacitracin— Proceed with Ointment as directed in the Assay for neomycin and in the Assay for bacitracin under Neomycin and Polymyxin B Sulfates and Bacitracin Zinc Ophthalmic Ointment.
Auxiliary Information— Please check for your question in the FAQs before contacting USP.
Topic/Question Contact Expert Committee
Monograph Ahalya Wise, M.S.
(MDANT05) Monograph Development-Antibiotics
Reference Standards Lili Wang, Technical Services Scientist
USP32–NF27 Page 3047
Pharmacopeial Forum: Volume No. 28(4) Page 1154