Neomycin Sulfate and Bacitracin Ointment

» Neomycin Sulfate and Bacitracin Ointment contains the equivalent of not less than 90.0 percent and not more than 130.0 percent of the labeled amounts of neomycin and bacitracin.

Packaging and storage— Preserve in tight, light-resistant containers, preferably at controlled room temperature.

USP Reference standards

—
USP Bacitracin Zinc RS.
USP Neomycin Sulfate RS.

Thin-layer chromatographic identification test

201BNP

: meets the requirements.

Minimum fill

755

: meets the requirements.

Water, Method I

921

: not more than 0.5%, 20 mL of a mixture of toluene and methanol (7:3) being used in place of methanol in the titration vessel.

Assay for neomycin— Proceed with Ointment as directed in the Assay under Neomycin Sulfate Ointment.

Assay for bacitracin— Proceed with Ointment as directed in the Assay under Bacitracin Ointment

Auxiliary Information— Please check for your question in the FAQs before contacting USP.

Topic/Question	Contact	Expert Committee
Monograph	Ahalya Wise, M.S. Scientist 1-301-816-8161	(MDANT05) Monograph Development-Antibiotics
Reference Standards	Lili Wang, Technical Services Scientist 1-301-816-8129 RSTech@usp.org

USP32–NF27 Page 3047

Pharmacopeial Forum: Volume No. 28(4) Page 1153