C8H4Na2O12Sb2 581.61

Antimonate(2-), bis[µ-[2,3-dihydroxybutanedioato(4-)-O1,O2:O3,O4]]di-, disodium, stereoisomer.
Disodium bis[µ-[l-(+)-tartrato(4-)]]diantimonate(2-) [34521-09-0].

Packaging and storage— Preserve in well-closed containers.

Identification— It responds to the tests for Antimony 191, for Sodium 191, and for Tartrate 191.

Acidity or alkalinity— Dissolve 1.0 g in 50 mL of carbon dioxide-free water, and titrate with 0.010 N hydrochloric acid or 0.010 N sodium hydroxide to a pH of 4.5: not more than 2.0 mL is required.

Loss on drying 731— Dry it at 105 to constant weight: it loses not more than 6.0% of its weight.

Arsenic, Method II 211: 8 ppm.

Lead 251: not more than 0.002%.

Assay— Dissolve about 500 mg of Antimony Sodium Tartrate, accurately weighed, in 50 mL of water, add 5 g of potassium sodium tartrate, 2 g of sodium borate, and 3 mL of starch TS, and immediately titrate with 0.1 N iodine VS to the production of a persistent blue color. Each mL of 0.1 N iodine is equivalent to 14.54 mg of C8H4Na2O12Sb2.

Topic/Question	Contact	Expert Committee
Monograph	Behnam Davani, Ph.D., M.B.A. Senior Scientist 1-301-816-8394	(MDAA05) Monograph Development-Antivirals and Antimicrobials

USP32–NF27 Page 1568