Hydrogen Peroxide Concentrate
Hydrogen peroxide [7722-84-1].
» Hydrogen Peroxide Concentrate contains not less than 29.0 percent and not more than 32.0 percent, by weight, of H2O2. It contains not more than 0.05 percent of a suitable preservative or preservatives.
CautionHydrogen Peroxide Concentrate is a strong oxidant.
Packaging and storage Preserve in partially-filled containers having a small vent in the closure, and store in a cool place.
Labeling Label it to indicate the name and amount of any added preservative. The label states that this article is not intended for direct administration to humans or animals.
Acidity Dilute 25 g with water to 250 mL, and mix thoroughly. Take 25 mL of the solution, add phenolphthalein TS, and titrate with 0.10 N sodium hydroxide: not more than 2.5 mL is required for neutralization.
Chloride 221: 1.5 g diluted with water to 25 mL shows no more chloride than 0.10 mL of 0.020 N hydrochloric acid (0.005%).
Other requirements It responds to the Identification test and meets the requirements of the tests for Nonvolatile residue, Heavy metals, and Limit of preservative (90 mL of it being used) under Hydrogen Peroxide Topical Solution.
Assay Accurately weigh about 1 mL of Concentrate in a tared 100-mL volumetric flask, dilute with water to volume, and mix. To 20.0 mL of this solution add 20 mL of 2 N sulfuric acid, and titrate with 0.1 N potassium permanganate VS. Each mL of 0.1 N potassium permanganate is equivalent to 1.701 mg of H2O2.
Auxiliary Information Please check for your question in the FAQs before contacting USP.
USP32NF27 Page 2587Pharmacopeial Forum: Volume No. 30(5) Page 1629