Aminohippuric Acid
194.19Glycine, N-(4-aminobenzoyl)-.
p-Aminohippuric acid
[61-78-9].» Aminohippuric Acid contains not less than 98.0 percent and not more than 100.5 percent of C9H10N2O3, calculated on the dried basis.
Packaging and storage—
Preserve in tight, light-resistant containers.
Identification—
B:
Dissolve about 10 mg in 5 mL of water, and add 0.5 mL of 3 N hydrochloric acid, 0.5 mL of sodium nitrite solution (1 in 10), and a solution of 0.20 g of 2-naphthol in 10 mL of 6 N ammonium hydroxide: a red color is produced.
Loss on drying 
731
—
Dry it at 105
for 2 hours: it loses not more than 0.25% of its weight.
731—
Dry it at 105 for 2 hours: it loses not more than 0.25% of its weight.
Residue on ignition 281:
not more than 0.25%.
281:
not more than 0.25%.
Heavy metals, Method II 231:
0.001%.
231:
0.001%.
Assay—
Transfer about 150 mg, accurately weighed, of Aminohippuric Acid to a beaker or a casserole. Add 5 mL of hydrochloric acid and 50 mL of water, and proceed as directed under Nitrite Titration 451, beginning with “stir until dissolved.” Each mL of 0.1 M sodium nitrite is equivalent to 19.42 mg of C9H10N2O3.
451, beginning with “stir until dissolved.” Each mL of 0.1 M sodium nitrite is equivalent to 19.42 mg of C9H10N2O3.
Auxiliary Information—
Please check for your question in the FAQs before contacting USP.
| Topic/Question | Contact | Expert Committee |
| Monograph | Larry N. Callahan, Ph.D.
Senior Scientist 1-301-816-8385 |
(BBPP05) Biologics and Biotechnology - Proteins and Polysaccharides |
| Reference Standards | Lili Wang, Technical Services Scientist 1-301-816-8129 RSTech@usp.org |
USP32–NF27 Page 1521