• British Pharmacopoeia Volume V
  • Appendices
  • Appendix I A. General Reagents

Chlorogenic Acid
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Chlorogenic Acid (1S,3R,4R,5R)-3-[(3,4-Dihydroxycinnamoyl)oxy]-1,4,5- trihydroxycyclohexanecarboxylic acid; C16H18O9 = 354.3 (327-97-9)

White or almost white, crystalline powder or needles, freely soluble in boiling water, in acetone and in ethanol (96%).

bp2013_v5_47_1003_[appendix_i_a]_c_ep7-7_ep_revised_texts [alpha]_26_d.png, about - 35.2.

Melting point, about 208°.

Chromatography Examined under the conditions described on Identification A in the monograph on Belladonna leaf dry extract, standardised (1294), the chromatogram shows only one principal zone.

Chlorogenic acid used in liquid chromatography complies with the following additional test.

Assay Liquid chromatography (2.2.29) as prescribed in the monograph on Artichoke Leaf (1866).

Content, minimum 97.0%.