• British Pharmacopoeia Volume IV
  • Appendices
  • Appendix I A. General Reagents

Protamine Sulphate
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Protamine Sulphate (53597-25-4 (salmine); 9007-31-2 (clupeine))

A mixture of the sulphates of basic peptides extracted from the sperm or roe of fish, usually species of Salmonidae or Clupeidae. It binds with heparin, inhibiting its anticoagulant activity.