*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : QK4247000
CHEMICAL NAME : 2-Naphthalenol, 1-((4-methyl-2-nitrophenyl)azo)-
CAS REGISTRY NUMBER : 2425-85-6
OTHER CAS REGISTRY NOS. : 12238-48-1
12240-01-6
12240-02-7
39310-30-0
LAST UPDATED : 199710
DATA ITEMS CITED : 16
MOLECULAR FORMULA : C17-H13-N3-O3
MOLECULAR WEIGHT : 307.33
WISWESSER LINE NOTATION : L66J BNUNR D1 BNW& CQ
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
SYNONYMS/TRADE NAMES :
* Accosperse Toluidine Red XL
* Adc Toluidine Red B
* Atlasol Spirit Red 3
* Calcotone Toluidine Red YP
* Carnelio Helio Red
* Cerven pigment 3
* Chromatex Red J
* C.I.12120
* C.I. Pigment Red 3
* C.P. Toluidine Toner A-2989
* C.P. Toluidine Toner A-2990
* C.P. Toluidine Toner Dark RS-3340
* C.P. Toluidine Toner Deep X-1865
* C.P. Toluidine Toner Light RS-3140
* C.P. Toluidine Toner RT-6101
* C.P. Toluidine Toner RT-6104
* Dainichi Permanent Red 4 R
* D and C Red No. 35
* Deep Fastona Red
* Duplex Toluidine Red L 20-3140
* Eljon Fast Scarlet PV Extra
* Eljon Fast Scarlet RN
* Enialit Light Red RL
* Fastona Red B
* Fastona Scarlet RL
* Fastona Scarlet YS
* Fast Red A (pigment)
* Fast Red AB
* Fast Red J
* Fast Red JE
* Fast Red R
* Graphtol Red A-4RL
* Hansa Red B
* Hansa Red G
* Hansa Scarlet RB
* Hansa Scarlet RN
* Hansa Scarlet RNC
* Helio Fast Red BN
* Helio Fast Red RL
* Helio Fast Red RN
* Helio Red RL
* Helio Red Toner
* Hispalit Fast Scarlet RN
* Independence Red
* Irgalite Fast Red P4R
* Irgalite Fast Scarlet RND
* Irgalite Red PV2
* Irgalite Red RNPX
* Irgalite Scarlet RB
* Isol Fast Red HB
* Isol Fast Red RNB
* Isol Fast Red RN2B
* Isol Fast Red RNG
* Isol Fast Red RN2G
* Isol Toluidine Red HB
* Isol Toluidine Red RNB
* Isol Toluidine Red RN2B
* Isol Toluidine Red RNG
* Isol Toluidine Red RN2G
* Kromon Helio Fast Red
* Kromon Helio Fast Red YS
* Lake Red 4R
* Lake Red 4RII
* Lithol Fast Scarlet RN
* Lutetia Fast Red 3R
* Lutetia Fast Scarlet RF
* Lutetia Fast Scarlet RJN
* 1-((4-Methyl-2-nitrophenyl)azo)-2-naphthalenol
* Monolite Fast Scarlet CA
* Monolite Fast Scarlet GSA
* Monolite Fast Scarlet RB
* Monolite Fast Scarlet RBA
* Monolite Fast Scarlet RN
* Monolite Fast Scarlet RNA
* Monolite Fast Scarlet RNV
* Monolite Fast Scarlet RT
* NCI-C60366
* 1-((2-Nitro-4-methylphenyl)azo)-2-naphthol
* 1-(o-Nitro-p-tolylazo)-2-naphthol
* No. 2 Forthfast Scarlet
* Oralith Red P4R
* Permanent Red 4R
* Pigment Red 3
* Pigment Red RL
* Pigment Ruby
* Pigment Scarlet
* Pigment Scarlet
* Pigment Scarlet B
* Pigment Scarlet N
* Pigment Scarlet R
* Polymo Red FGN
* Recolite Fast Red RBL
* Recolite Fast Red BL
* Recolite Fast Red RYL
* Sanyo Scarlet Pure
* Sanyo Scarlet Pure No. 1000
* Scarlet pigment RN
* Segnale Light Red B
* Segnale Light Red 2B
* Segnale Light Red BR
* Segnale Light Red C4R
* Segnale Light Red RL
* Siegle Red 1
* Siegle Red B
* Siegle Red BB
* Silogomma Red RLL
* Silosol Red RBN
* Silosol Red RN
* Siloton Red BRLL
* Siloton Red RLL
* Symuler Fast Scarlet 4R
* Syton Fast Scarlet RB
* Syton Fast Scarlet RD
* Syton Fast Scarlet RN
* Tertropigment Red HAB
* Tertropigment Scarlet LRN
* Toluidine Red
* Toluidine Red 10451
* Toluidine Red 3B
* Toluidine Red BFB
* Toluidine Red BFGG
* Toluidine Red D 28-3930
* Toluidine Red Light
* Toluidine Red M 20-3785
* Toluidine Red R
* Toluidine Red 4R
* Toluidine Red RT-115
* Toluidine Red Toner
* Toluidine Red XL 20-3050
* Toluidine Toner
* Toluidine Toner Dark 5040
* Toluidine Toner 4R X-2700
* Toluidine Toner HR X-2741
* Toluidine Toner Keep HR X-2742
* Toluidine Toner L 20-3300
* Toluidine Toner RT-252
* Versal Scarlet PRNL
* Versal Scarlet RNL
* Vulcafor Scarlet A
*** HEALTH HAZARD DATA ***
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 42 gm/kg/14D-C
TOXIC EFFECTS :
Blood - normocytic anemia
Blood - changes in other cell count (unspecified)
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year:
27,793,1989
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 68 gm/kg/90D-C
TOXIC EFFECTS :
Liver - changes in liver weight
Kidney, Ureter, Bladder - changes in bladder weight
Blood - changes in bone marrow (not otherwise specified)
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year:
27,793,1989
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 84 gm/kg/2W-C
TOXIC EFFECTS :
Liver - changes in liver weight
Blood - changes in erythrocyte (RBC) count
Nutritional and Gross Metabolic - other changes
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-407,1992
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 273 gm/kg/13W-C
TOXIC EFFECTS :
Liver - changes in liver weight
Related to Chronic Data - death
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-407,1992
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 910 gm/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Liver - tumors
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-407,1992
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 4368 gm/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Liver - tumors
Kidney, Ureter, Bladder - tumors
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-407,1992
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 3333 ug/plate
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For
publisher information, see EMMUEG. Volume(issue)/page/year: 8(Suppl
7),1,1986
*** REVIEWS ***
IARC Cancer Review:Animal Limited Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 57,259,1993
IARC Cancer Review:Human Inadequate Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 57,259,1993
IARC Cancer Review:Group 3
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 57,259,1993
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - M2109
No. of Facilities: 6944 (estimated)
No. of Industries: 78
No. of Occupations: 56
No. of Employees: 47730 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - M2109
No. of Facilities: 4689 (estimated)
No. of Industries: 57
No. of Occupations: 53
No. of Employees: 51931 (estimated)
No. of Female Employees: 11615 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
NTP Carcinogenesis Studies (feed);some evidence:mouse,rat
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-407,92
*** END OF RECORD ***