*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YT5775000
CHEMICAL NAME           : Urea, (2-isopropyl-4-pentenoyl)-
CAS REGISTRY NUMBER     : 528-92-7
BEILSTEIN REFERENCE NO. : 1775529
REFERENCE               : 4-03-00-00120 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C9-H16-N2-O2
MOLECULAR WEIGHT        : 184.27
WISWESSER LINE NOTATION : ZVMVY2U1&Y1&1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Allylisopropylacetylcarbamide
   * Allylisopropylacetylurea
   * N-(Aminocarbonyl)-2-(1-methylethyl)-4-pentenamide
   * Apronal
   * Apronalide
   * Isodormid
   * Isopropylallylazetylkarbamid
   * (2-Isopropyl-4-pentenoyl)urea
   * Sedormid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1050 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 19,323,1980
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPHAA3 Journal of the American Pharmaceutical Association.  (Washington, DC)
    V.1-28, 1912-39; New series: V.1-17, 1961-77. Volume(issue)/page/year:
   23,788,1934
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1220 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 19,323,1980
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DMWOAX Deutsche Medizinische Wochenschrift.  (Stuttgart, Fed. Rep. Ger.)
   V.1-104, 1875-1979.  Volume(issue)/page/year: 54,1166,1928
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DMWOAX Deutsche Medizinische Wochenschrift.  (Stuttgart, Fed. Rep. Ger.)
   V.1-104, 1875-1979.  Volume(issue)/page/year: 54,1166,1928
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DMWOAX Deutsche Medizinische Wochenschrift.  (Stuttgart, Fed. Rep. Ger.)
   V.1-104, 1875-1979.  Volume(issue)/page/year: 54,1166,1928
 
                            *** END OF RECORD ***