Indalpine
Structural Formula Vector Image
Title: Indalpine
CAS Registry Number: 63758-79-2
CAS Name: 3-[2-(4-Piperidinyl)ethyl]-1H-indole
Additional Names: 4-[2-(3-indolyl)ethyl]piperidine
Manufacturers' Codes: LM-5008
Trademarks: Upstene (Pharmuka)
Molecular Formula: C15H20N2
Molecular Weight: 228.33
Percent Composition: C 78.90%, H 8.83%, N 12.27%
Literature References: Selective serotonin uptake inhibitor. Prepn: A. A. Champseix et al., DE 2618152; eidem, US 4064255 (both 1977 to Mar-Pha Soc. Etud. Exploit. Marques). HPLC determn: C. Jozefczak et al., J. Chromatogr. 230, 87 (1982). Spectrofluorimetric determn and clinical pharmacology: A. Iliopoulou et al., Pharmatherapeutica 2, 613 (1981). Pharmacology: G. LeFur et al., Life Sci. 23, 1959 (1978); C. Gueremy et al., J. Med. Chem. 23, 1306 (1980); R. Ashkenazi et al., Br. J. Pharmacol. 79, 765, 915 (1983). Clinical study: A. Wauters, Acta Psychiatr. Belg. 83, 69 (1983).
 
Derivative Type: Monohydrochloride
Molecular Formula: C15H20N2.HCl
Molecular Weight: 264.79
Percent Composition: C 68.04%, H 7.99%, N 10.58%, Cl 13.39%
Properties: mp 167°.
Melting point: mp 167°
 
Therap-Cat: Antidepressant.
Keywords: Antidepressant; Bicyclics; Serotonin Uptake Inhibitor.

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