Structural Formula Vector Image
Title: IMPA
CAS Registry Number: 1832-54-8
CAS Name: Methylphosphonic acid mono(1-methylethyl) ester
Additional Names: iPMPA; O-isopropyl methyl phosphonic acid; neutralized sarin
Molecular Formula: C4H11O3P
Molecular Weight: 138.10
Percent Composition: C 34.79%, H 8.03%, O 34.76%, P 22.43%
Literature References: Degradation product of the nerve gas, sarin, q.v. Identification as hydrolysis product: F. C. G. Hoskin, Can. J. Biochem. Physiol. 34, 75 (1956). Prepn as silver salt: idem, Can. J. Chem. 35, 581 (1957); of ester: J. I. G. Cadogan et al., J. Chem. Soc. 1971, 1988. Biodisposition in mice: P. J. Little et al., Toxicol. Appl. Pharmacol. 83, 412 (1986). Biological monitoring in human urine after sarin exposure: M. Minami et al., J. Toxicol. Sci. 23, Suppl. II, 250 (1998). Biodegradation: Y. Zhang et al., Biotechnol. Bioeng. 64, 221 (1999). Determn in ground water by GC with flame photometric detection: G. A. Sega et al., J. Chromatogr. A 790, 143 (1997); LC-MS rapid determn: R. W. Read, R. M. Black, ibid. 862, 169 (1999).
Properties: bp0.02 88°. nD25 1.4210.
Boiling point: bp0.02 88°
Index of refraction: nD25 1.4210
Use: Marker for the detection of sarin.

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