Imidocarb
Structural Formula Vector Image
Title: Imidocarb
CAS Registry Number: 27885-92-3
CAS Name: N,N¢-Bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea
Additional Names: 3,3¢-di-2-imidazolin-2-ylcarbanilide
Molecular Formula: C19H20N6O
Molecular Weight: 348.40
Percent Composition: C 65.50%, H 5.79%, N 24.12%, O 4.59%
Literature References: Prepn: GB 1007334; R. Fischer, R. Hirt, US 3338917 (1965, 1967 both to Wander). Babesicidal effect in mice and rats: G. Schmidt et al., Res. Vet. Sci. 10, 530 (1969); E. Beveridge, ibid. 534. Effect on exptl anaplasmosis in calves: T. O. Roby, ibid. 13, 519 (1972). Comparison of the dipropionate and tetracycline, q.v., in canine ehrlichiosis: J. E. Price, T. T. Dolan, Vet. Rec. 107, 275 (1980). Efficacy in Babesia felis infection: F. T. Potgieter, J. S. Afr. Vet. Assoc. 52, 289 (1981). Effect on B. ovis infection in sheep: S. A. Michael, A. H. El Refaii, Trop. Anim. Health Prod. 14, 1 (1982), C.A. 96, 192991 (1982).
 
Derivative Type: Dihydrochloride
CAS Registry Number: 5318-76-3
Additional Names: Imizocarb
Manufacturers' Codes: 4A65
Molecular Formula: C19H20N6O.2HCl
Molecular Weight: 421.32
Percent Composition: C 54.16%, H 5.26%, N 19.95%, O 3.80%, Cl 16.83%
Properties: Solid, mp 350° (dec). LD50 in mice, rats (mg/kg): 107, 150 s.c. (Beveridge).
Melting point: mp 350° (dec)
Toxicity data: LD50 in mice, rats (mg/kg): 107, 150 s.c. (Beveridge)
 
Derivative Type: Dipropionate
Additional Names: Imizol
Trademarks: Imizad Equine Injection (Burroughs Wellcome)
Molecular Formula: C25H32N6O7
Molecular Weight: 528.56
Percent Composition: C 56.81%, H 6.10%, N 15.90%, O 21.19%
 
Therap-Cat-Vet: Antiprotozoal (Babesia).

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