Ethylenediamine
Structural Formula Vector Image
Title: Ethylenediamine
CAS Registry Number: 107-15-3
CAS Name: 1,2-Ethanediamine
Additional Names: 1,2-diaminoethane
Molecular Formula: C2H8N2
Molecular Weight: 60.10
Percent Composition: C 39.97%, H 13.42%, N 46.61%
Line Formula: H2NCH2CH2NH2
Literature References: Manuf from ethylene dichloride and ammonia: Faith, Keyes & Clark's Industrial Chemicals, F. A. Lowenheim, M. K. Moran, Eds. (Wiley-Interscience, New York, 4th ed., 1975) pp 385-388. Toxicity: H. F. Smyth et al., J. Ind. Hyg. Toxicol. 23, 259 (1941).
Properties: Colorless, clear, thick liq; ammonia odor. d425 0.898. bp 116-117°. mp 8.5°. nD26 1.4540. Flash pt, closed cup: 110°F (43°C). Volatile with steam. Freely sol in water forming a hydrate, also in alcohol; slightly sol in ether; sol in benzene unless insufficiently dried: S. G. Boas-Traube et al., Nature 162, 960 (1948). Note: Strongly alkaline and may readily absorb CO2 from air to form a nonvolatile carbonate. Protect against undue exposure to the atmosphere. LD50 orally in rats: 1.16 g/kg (Smyth).
Melting point: mp 8.5°
Boiling point: bp 116-117°
Flash point: Flash pt, closed cup: 110°F (43°C)
Index of refraction: nD26 1.4540
Density: d425 0.898
Toxicity data: LD50 orally in rats: 1.16 g/kg (Smyth)
 
Derivative Type: Monohydrate
Properties: mp 10°; bp 118°.
Melting point: mp 10°
Boiling point: bp 118°
 
Derivative Type: Dihydrochloride
Molecular Formula: C2H8N2.2HCl
Molecular Weight: 133.02
Percent Composition: C 18.06%, H 7.58%, N 21.06%, Cl 53.30%
Properties: Crystals. Sublimes without melting. Freely sol in water. Practically insol in alcohol. Aq soln is practically neutral.
 
CAUTION: Potential symptoms of overexposure to ethylenediamine are irritation of nose, respiratory system; sensitization dermatitis; asthma; liver and kidney damage. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 136.
Use: Solvent for casein, albumin, shellac, and sulfur; emulsifier; stabilizing rubber latex; as inhibitor in antifreeze solns; in textile lubricants. Pharmaceutic aid (aminophylline injection stabilizer).
Therap-Cat-Vet: Dihydrochloride has been used as a urinary acidifier.

Other Monographs:
Aluminum IsopropoxideThiazole OrangeHomovanillic AcidEndorphins
QuinalizarinHydroxychloroquineClometocillinDimethyl Sulfoxide
Hydroxypropyl CelluloseSodium MetaphosphateHarmalineDimetridazole
Colesevelam HydrochlorideUranyl NitratePiperocaineLigroin
©2006-2023 DrugFuture->Chemical Index Database