Daltroban
Structural Formula Vector Image
Title: Daltroban
CAS Registry Number: 79094-20-5
CAS Name: 4-[2-[[(4-Chlorophenyl)sulfonyl]amino]ethyl]benzeneacetic acid
Additional Names: [p-[2-(p-chlorobenzenesulfonamido)ethyl]phenyl]acetic acid
Manufacturers' Codes: BM-13505; SKF-96148
Molecular Formula: C16H16ClNO4S
Molecular Weight: 353.82
Percent Composition: C 54.31%, H 4.56%, Cl 10.02%, N 3.96%, O 18.09%, S 9.06%
Literature References: Thromboxane A2-receptor antagonist. Prepn: E. C. Witte et al., DE 3000377; eidem, US 4443477 (1981, 1984 both to Boehringer, Mann.). Receptor binding study: A. Yanagisawa et al., Eur. J. Pharmacol. 133, 89 (1987). Pharmacological evaluations in animals: D. J. Lefer et al., Arch. Int. Pharmacodyn. 287, 89 (1987); E. F. Smith, III, J. McDonald, Pharmacology 36, 340 (1988); P. Löbel et al., Biomed. Biochim. Acta 47, S 86 (1988). GC determn in biological fluids: V. Uebis, J. Chromatogr. 419, 345 (1987).
Therap-Cat: Antithrombotic.
Keywords: Antithrombotic; Thromboxane A2-Receptor Antagonist.

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