Primaquine
Structural Formula Vector Image
Title: Primaquine
CAS Registry Number: 90-34-6
CAS Name: N4-(6-Methoxy-8-quinolinyl)-1,4-pentanediamine
Additional Names: 8-(4-amino-1-methylbutylamino)-6-methoxyquinoline
Manufacturers' Codes: SN-13272
Molecular Formula: C15H21N3O
Molecular Weight: 259.35
Percent Composition: C 69.47%, H 8.16%, N 16.20%, O 6.17%
Literature References: Prepn following the synthesis of pamaquine: Elderfield et al., J. Am. Chem. Soc. 68, 1525 (1946); improved procedure: Elderfield et al., ibid. 77, 4816 (1955). Review: Olenick in Antibiotics vol. 3, J. W. Corcoran, F. E. Hahn, Eds. (Springer-Verlag, New York, 1975) pp 516-520.
Properties: Viscous liquid, bp0.2 175-179°. Soluble in ether.
Boiling point: bp0.2 175-179°
 
Derivative Type: Diphosphate
CAS Registry Number: 63-45-6
Molecular Formula: C15H21N3O.2H3PO4
Molecular Weight: 455.34
Percent Composition: C 39.57%, H 5.98%, N 9.23%, O 31.62%, P 13.60%
Properties: Yellow crystals from 90% ethanol, mp 197-198°. Moderately sol in water.
Melting point: mp 197-198°
 
Derivative Type: Oxalate
Molecular Formula: C15H21N3O.C2H2O4
Molecular Weight: 349.38
Percent Composition: C 58.44%, H 6.64%, N 12.03%, O 22.90%
Properties: Yellow crystals from 80% ethanol, mp 182.5-185°.
Melting point: mp 182.5-185°
 
Therap-Cat: Antimalarial.
Keywords: Antimalarial.

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