Aminobenzoate Potassium Tablets
» Aminobenzoate Potassium Tablets contain not less than 90.0 percent and not more than 110.0 percent of the labeled amount of aminobenzoate potassium (C7H6 KNO2).
Packaging and storage
Preserve in well-closed containers.
Identification
Proceed as directed for Aminobenzoate Potassium Capsules, using 1 g of finely powdered Tablets.
Dissolution 711
Medium:
water; 900 mL.
Apparatus 1:
100 rpm.
Time:
45 minutes.
Procedure
Determine the amount of C7H6KNO2 dissolved by employing UV absorption at the wavelength of maximum absorbance at about 270 nm on filtered portions of the solution under test, suitably diluted with Medium, in comparison with a Standard solution having a known concentration of USP Aminobenzoate Potassium RS in the same Medium.
Tolerances
Not less than 75% (Q) of the labeled amount of C7H6KNO2 is dissolved in 45 minutes.
Uniformity of dosage units 905:
meet the requirements.
Assay
Standard preparation
Prepare a solution of USP Aminobenzoate Potassium RS having a known concentration of about 5 µg per mL.
Assay preparation
and ProcedureWeigh and finely powder not fewer than 20 Tablets. Using a portion of the powdered Tablets, equivalent to about 100 mg of aminobenzoate potassium, proceed as directed in the Assay under Aminobenzoate Potassium Capsules.
Auxiliary Information
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USP32NF27 Page 1515
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